Metabolic Peptide
Mitochondrial ORF of the 12S rRNA type-c
MRWQEMGYIFYPRKLR
A mitochondrial-derived peptide that modulates metabolic processes, with significant implications for exercise metabolism observed in rodent studies. Premium Research Peptide.
Third Party Tested by Freedom Diagnostics
Technical specifications
Extremely temperature sensitive
Store frozen until use
Reconstitute immediately before injection
Lyophilized (powder)
-20°C • stable long-term
Reconstituted
2-8°C • use immediately
Room temperature
Degrades 85-90% in 2-3 hrs
Peer-reviewed research
Cell Metabolism
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity...
2015 • DOI: 10.1016/j.cm...
PMID: 25738459
Lee C, Zeng J, Drew BG et al.
Nature Communications
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and...
2021 • DOI: 10.1038/s41467-020-20790...
Reynolds JC, Lai RW, Woodhead JST et...
Alzheimer's Drug Discovery Foundation
MOTS-c Cognitive Vitality Report
2021
ADDF Aging and Alzheimer's
Aging Cell
The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?
2015 • DOI: 10.1111/acel.1...
PMID: 26289118
Fuku N, Pareja-Galeano H, Zempo H e...
Physiol Rep
The mitochondrial-derived peptide MOTS-c is a regulator of plasma metabolites and enhances insulin...
2019 • PMID: 31293078
Kim S-J, Miller B, Mehta HH et al.
Biochemical and Biophysical Research Communications
Mitochondria related peptide MOTS-c suppresses ovariectomy-induced bone loss via AMPK activation
2016
Ming W, Lu G, Xin S et al.
Pediatric Diabetes
Circulating MOTS-c levels are decreased in obese male children and adolescents and associated with...
2018
Du C, Zhang C, Wu W et al.
ClinicalTrials.gov
Study of CB4211 in Patients With Nonalcoholic Fatty Liver Disease (NAFLD) and Obesity
2019
CohBar, Inc.
