Plasma Concentration Studies

SELANK

TP-7

Thr-Lys-Pro-Arg-Pro-Gly-Pro

CAS: 129954-34-3

A 7-amino acid synthetic heptapeptide derived from tuftsin that modulates GABAergic neurotransmission and BDNF expression, studied for anxiolytic and nootropic effects in clinical research. Premium Research Peptide.TP-7

Certificate of Analysis

Third Party Tested by Freedom Diagnostics

99.42%
Purity
Variant
Selank 10mg
Lot #
Green Cap
Labeled
10mg
Actual
12.94 mg
Tested
Apr 14, 2026

Compound Information

Technical specifications

🔬 Molecular Profile

What Is Selank?

Synthetic heptapeptide analog of tuftsin, an immunomodulatory tetrapeptide derived from IgG

Heptapeptide

Tuftsin Analog

Type
Synthetic heptapeptide
CAS Number
129954-34-3
Molecular Formula
C33H57N11O9
Molecular Weight
751.9 g/mol
Amino Acids
7 residues
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
🧊 Storage Requirements

Stability Information

Handle with care to maintain potency

Light sensitive

Temperature sensitive

Lyophilized (powder)

-20°C • up to 2 years

Reconstituted

2-8°C • use within 4 weeks

Nasal spray (0.15%)

2-8°C • 30 days after opening

📋 Development Status

Regulatory Information

Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences

Developer
Russian Academy of Sciences
Collaborator
V.V. Zakusov Institute
Approval
Russia (2009), Ukraine
Indication
Generalized Anxiety Disorder
US Status
Not FDA-approved
Formulation
0.15% nasal drops (Rx in Russia)

Sources & References

Peer-reviewed research

Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova

Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized...

2008

PMID: 18454096

Zozulia AA, Neznamov GG, Siuniakov...

Behavioural Neurology

Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress...

2017 • DOI: 10.1155/2017

PMID: 28280289

Kasian A, Kolomin T, Andreeva L, et al.

Frontiers in Pharmacology

Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission

2016 • DOI: 10.3389/fph...

PMID: 26924987

Volkova A, Shadrina M, Kolomin T, et al.

Bulletin of Experimental Biology and Medicine

Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating...

2019 • PMID: 31625062

Kozlovskii II, Andreeva LA, Myasoedov...

Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova

A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of...

2014 • PMID: 25176261

Medvedev VE, Tereshchenko ON,...

Bulletin of Experimental Biology and Medicine

The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic...

2001 • PMID: 11550013

Zozulya AA, Kost NV, Yu Sokolov O, et...

Bulletin of Experimental Biology and Medicine

The Influence of Selank on the Level of Cytokines Under Conditions of Experimental Immunodeficiency

2020 • PMID: 32621722

Pharmacokinetic Data

Selank Intranasal Bioavailability Studies

PubChem Database

Selank - Compound Summary

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