Plasma Concentration Studies
ACTH (4-10)
ACTH (4-7)-Pro-Gly-Pro
Met-Glu-His-Phe-Pro-Gly-Pro
MEHFPGP
CAS: 80714-61-0
A 7-amino acid synthetic heptapeptide analog of ACTH (4-10) that upregulates BDNF expression and modulates the TrkB signaling pathway, studied for cognitive enhancement and neuroprotection in clinical research. Premium Research Peptide.
Third Party Tested by Freedom Diagnostics
Technical specifications
Synthetic heptapeptide analog of ACTH (4-10) with C-terminal Pro-Gly-Pro extension for enhanced stability
Heptapeptide
ACTH Analog
Handle with care to maintain potency
Light sensitive
Temperature sensitive
Lyophilized (powder)
-20°C • up to 2 years
Reconstituted
2-8°C • use within 4 weeks
Nasal spray (0.15%)
2-8°C • 30 days after opening
Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences
Peer-reviewed research
Brain Research
Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat...
2006 • DOI: 10.1016/j.bra...
PMID: 16996037
Dolotov OV, Karpenko EA, Inozemtseva
BMC Genomics
The peptide semax affects the expression of genes related to the immune and vascular systems in rat...
2014 • DOI: 10.1186/1471-...
PMID: 24661656
Medvedeva EV, Dmitrieva VG,
Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova
The efficacy of semax in the treatment of patients at different stages of ischemic stroke
2018
PMID: 29798983
Journal of Molecular Neuroscience
Comparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus,...
2010 • DOI: 10.1007/s120...
PMID: 19662538
Shadrina M, Kolomin T, Agapova T, et...
International Journal of Molecular Sciences
Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Molecular Level
2020
PMID: 32575851
Alzheimer's Drug Discovery Foundation
Semax - Cognitive Vitality For Researchers
PubChem Database
Semax - Compound Summary (CID 9811102)
